Advanced Evidence Synthesis
Methodological support aligned with top-tier medical and health journals
Tier 1
Tier 1: Systematic Review & Meta-Analysis
The essential standard for high-impact publicationA complete, PRISMA-compliant systematic review and pairwise meta-analysis designed for Q1/Q2 journals.
Includes:
- PRISMA-compliant systematic search & screening
- Risk of bias assessment (Cochrane/ROBINS-I)
- Pairwise meta-analysis (Random/Fixed effects)
- Subgroup & sensitivity analyses
- Publication bias assessment (Egger's/Funnel plots)
- GRADE certainty of evidence assessment
Best For: Ideal for standard clinical or observational studies.
Most Popular
Tier 2
Tier 2: Advanced Meta-Regression
Our Core Offering for Complex DataGoes beyond basic pooling to explore sources of heterogeneity through univariable and multivariable meta-regression.
Includes:
- Everything in Tier 1
- Univariable & Multivariable Meta-regression
- Moderator analysis (dosage, duration, intensity)
- Advanced heterogeneity interpretation
- Reviewer-response statistical support
Best For: Recommended for Frontiers, Nutrients, and broad-scope clinical papers.
Tier 3
Tier 3: Bayesian Network Meta-Analysis
Elite Methodological rigorCompare multiple interventions simultaneously using advanced Bayesian modeling.
Includes:
- Systematic review & network construction
- Bayesian NMA modeling (consistency/inconsistency models)
- Treatment ranking (SUCRA / P-scores)
- Transitivity & coherence assessment
- Node-splitting analysis for inconsistency
- GRADE for Network Meta-Analysis
Best For: Required for high-impact comparative effectiveness research.
Tier 4
Tier 4: Complex NMA + Regression
The Gold Standard of Evidence SynthesisThe most sophisticated analysis available, combining network modeling with covariate adjustment.
Includes:
- Everything in Tier 3 (NMA)
- Network Meta-Regression (NMR)
- Adjustment for baseline risk & effect modifiers
- Sensitivity analyses under different priors
- Extended multi-journal submission support
Best For: For funded projects and top-tier institutional research.
Topic Development Services
Client-Proposed Topic
You provide the research question and PICO. We validate feasibility and alignment.
Included in Package
Consultant-Proposed Topic
We identify a research gap, validate publishability, and propose a high-value topic.
Development Fee Applies (Credited if commissioned)